Dan I. Lebovic — Endo Lab

other 2013

Fertility and sterility ·doi:10.1016/j.fertnstert.2013.07.010

observational 2013

The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey

Human Reproduction ·doi:10.1093/humrep/det284

STUDY QUESTION: To what extent do the management of endometriosis and the symptoms that remain after treatment affect the quality of life in women with the disease? SUMMARY ANSWER: Many women with endometriosis had impaired quality of life…

observational 2012

The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres

Human Reproduction ·doi:10.1093/humrep/des073

BACKGROUND: This study aimed to calculate costs and health-related quality of life of women with endometriosis-associated symptoms treated in referral centres. METHODS: A prospective, multi-centre, questionnaire-based survey measured costs…

review 2011

Clinical management of endometriosis

Obstetrics and gynecology ·doi:10.1097/aog.0b013e31822adfd1

Endometriosis is a relatively common chronic gynecologic disorder that usually presents with chronic pelvic pain or infertility. The societal effect of this disorder is enormous both in monetary costs and in quality of life. The diagnosis o…

lab-animal 2010

Development and prevention of postsurgical adhesions in a chimeric mouse model of experimental endometriosis

Fertility and sterility ·doi:10.1016/j.fertnstert.2010.09.017

OBJECTIVE: To examine the impact of a recent surgery on development of endometriosis-related adhesions in a chimeric model and to determine the therapeutic efficacy of pioglitazone (PIO). DESIGN: Human endometrial biopsies were maintained …

other 2010

Peroxisome proliferator-activated receptor-(gamma) receptor ligand partially prevents the development of endometrial explants in baboons: a prospective, randomized, placebo-controlled study

Endocrinology ·doi:10.1210/en.2009-1076

A prospective, randomized, placebo-controlled study was conducted in a baboon model to determine if a thiazolidinedione agonist of peroxisome proliferator-activated receptor-gamma, pioglitazone, can impede the development of endometriosis. …

observational 2010

Public perceptions of endometriosis: perspectives from both genders

Acta obstetricia et gynecologica Scandinavica ·doi:10.3109/00016341003657900

OBJECTIVE: Many women with endometriosis experience significant delay between the onset of symptoms and definitive diagnosis. Much is published on physician awareness of endometriosis and on the experiences of women with the condition. Ther…

2010

Public perceptions of endometriosis: perspectives from both genders

other 2009

Endometriosis

·doi:10.1016/b978-1-4160-4907-4.00024-3

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare …

review 2009

Endometriosis-associated nerve fibers and pain

Acta obstetricia et gynecologica Scandinavica ·doi:10.1080/00016340903176826

The assessment and diagnosis of endometriosis remain elusive targets. Patient and medical-related factors add to delays in the detection and treatment. Recently, investigators have revealed specific nerve fibers present in endometriotic tis…

2009

Faculty Opinions recommendation of Comparison of contraceptive ring and patch for the treatment of symptomatic endometriosis.

·doi:10.3410/f.1159973.620232

2009

Faculty Opinions recommendation of Downregulation of CD36 results in reduced phagocytic ability of peritoneal macrophages of women with endometriosis.

·doi:10.3410/f.1163039.623688

2009

Faculty Opinions recommendation of Ectopic endometrium in human foetuses is a common event and sustains the theory of müllerianosis in the pathogenesis of endometriosis, a disease that predisposes to cancer.

·doi:10.3410/f.1160737.621404

2009

Faculty Opinions recommendation of Experimental endometriosis in immunocompromised mice after adoptive transfer of human leukocytes.

·doi:10.3410/f.1162825.624436

2009

Faculty Opinions recommendation of Experimental murine endometriosis induces DNA methylation and altered gene expression in eutopic endometrium.

·doi:10.3410/f.1147329.618297

2009

Faculty Opinions recommendation of Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis.

·doi:10.3410/f.1164690.626495

lab-animal 2009

Peroxisome-proliferator activator receptor-gamma activation decreases attachment of endometrial cells to peritoneal mesothelial cells in an in vitro model of the early endometriotic lesion

Molecular human reproduction ·doi:10.1093/molehr/gap061

The aim of this study was to investigate whether peroxisome proliferator-activated receptor (PPAR)-gamma activation has an effect on the attachment of endometrial cells to peritoneal mesothelial cells in a well-established in vitro model of…

2009

PPAR-gamma ligand activation decreases p450 aromatase gene expression in human endometriotic epithelial and stromal cells in vitro

·doi:10.1016/j.fertnstert.2009.07.046

nonrandomized-trial 2009

Thiazolidinediones as therapy for endometriosis: a case series

Gynecologic and obstetric investigation ·doi:10.1159/000230713

BACKGROUND: Current medical therapies for endometriosis result in delayed conception and have not been shown to provide any fertile benefit subsequent to treatment. Thiazolidinediones (TZDs) do not impede conception and have been shown to r…

2008

Faculty Opinions recommendation of A pilot study to evaluate the clinical relevance of endometriosis-associated nerve fibers in peritoneal endometriotic lesions.

·doi:10.3410/f.1138041.595155

2008

Faculty Opinions recommendation of Endometriosis and infertility Surgery and ART: An integrated approach for successful management.

·doi:10.3410/f.1116126.572108

2008

Faculty Opinions recommendation of In vitro fertilization in normoresponder patients with endometriomas: comparison with basal simple ovarian cysts.

·doi:10.3410/f.1106028.562152

2008

Faculty Opinions recommendation of Peroxisome proliferator-activated receptor-gamma ligand reduced tumor necrosis factor-alpha-induced interleukin-8 production and growth in endometriotic stromal cells.

·doi:10.3410/f.1102279.558306

2008

Faculty Opinions recommendation of The frequency of ovulation from the affected ovary decreases following laparoscopic cystectomy in infertile women with unilateral endometrioma during a natural cycle.

·doi:10.3410/f.1124147.581282

observational 2008

Periodontal disease and endometriosis: analysis of the National Health and Nutrition Examination Survey

Fertility and sterility ·doi:10.1016/j.fertnstert.2007.12.075

OBJECTIVE: To investigate whether an association exists between endometriosis and periodontal disease, because endometriosis and periodontal disease are chronic, inflammatory processes more common in patients with systemic autoimmune disord…