Peter Noertersheuser

ORCID: 0000-0002-3938-3040 · 7 papers in corpus
other 2021
Clinical and translational science ·doi:10.1111/cts.13006

Decline of bone mineral density (BMD) during menopause is related to increased risk of fractures in postmenopausal women, however, this relationship in premenopausal women has not been established. To quantify this relationship, real-world …

other 2021
Clinical pharmacokinetics ·doi:10.1007/s40262-021-01096-w

BACKGROUND AND OBJECTIVES: Elagolix is an orally active, gonadotropin-releasing hormone receptor antagonist approved for the management of endometriosis-associated pain and heavy menstrual bleeding associated with uterine fibroids. Elagolix…

other 2021
Clinical and translational science ·doi:10.1111/cts.13040

Elagolix is a novel, oral gonadotropin-releasing hormone receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis and heavy menstrual bleeding associated with uterine fibroids. Consistent wit…

review 2020
Clinical pharmacokinetics ·doi:10.1007/s40262-019-00840-7

The clinical pharmacology of elagolix was extensively evaluated in clinical studies in healthy subjects and in women with endometriosis. Elagolix pharmacokinetics (PK) show significant population variability, however they are minimally affe…

other 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12545

Elagolix is an oral gonadotropin-releasing hormone antagonist approved by the US Food and Drug Administration (FDA) for the management of moderate-to-severe pain associated with endometriosis and in combination with estradiol/norethindrone …

nonrandomized-trial 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12560

Elagolix is a novel oral gonadotropin releasing hormone receptor antagonist, that can suppress estradiol in a dose-dependent manner. It is indicated for management of moderate-to-severe pain associated with endometriosis. A population expos…

other 2018
Clinical pharmacokinetics ·doi:10.1007/s40262-018-0629-6

INTRODUCTION: Elagolix is a novel, orally active, non-peptide, competitive gonadotropin-releasing hormone (GnRH) receptor antagonist in development for the management of endometriosis with associated pain and heavy menstrual bleeding due to…