Jianxin Sun

No ORCID on file · 5 papers in corpus
lab-animal 2026
The Journal of clinical investigation ·doi:10.1172/jci178862

Defective endometrial decidualization is one major cause of female infertility, yet the underlying mechanisms remain elusive. Here, we identified that protein arginine methyltransferase 5 (PRMT5), which was upregulated during decidualizatio…

lab-animal 2023
EBioMedicine ·doi:10.1016/j.ebiom.2022.104433

BACKGROUND: Successful embryo implantation requires the attachment of a blastocyst to the receptive endometrial epithelium, which was disturbed in the women with recurrent implantation failure (RIF). Endometrial β3-integrin was the most imp…

lab-animal 2019
EBioMedicine ·doi:10.1016/j.ebiom.2019.10.018

BACKGROUND: Recurrent implantation failure (RIF) remains a critical and challenging problem in assisted reproductive technology mainly due to impaired decidualization. The endocytic and transcytotic activity in the endometrium are crucial f…

lab-animal 2017
Cell death discovery ·doi:10.1038/cddiscovery.2017.57

HOXA10 has emerged as an important molecular marker of endometrial receptivity. Recurrent implantation failure (RIF) after in vitro fertilization-embryo transplantation (IVF-ET) treatment is associated with impaired endometrial receptivity,…

lab-animal 2017
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0243-8

BACKGROUND: Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal cells (hESCs), Krüp…