Lach J

ORCID: 0000-0002-4284-6827 · 2 papers in corpus

other 2025

A comprehensive analysis of the uterine microbiome in endometrial cancer patients - identification of Anaerococcus as a potential biomarker and carcinogenic cofactor

Frontiers in cellular and infection microbiology ·doi:10.3389/fcimb.2025.1511625

INTRODUCTION: Endometrial cancer (EC) is a significant gynecological malignancy with increasing incidence worldwide. Emerging evidence highlights the role of the uterine microbiome in the pathogenesis of EC. This study aims to characterize …

observational 2021

AHR-dependent genes and response to MTX therapy in rheumatoid arthritis patients

The pharmacogenomics journal ·doi:10.1038/s41397-021-00238-4

Methotrexate (MTX) is the first-line therapy for rheumatoid arthritis. Nevertheless, MTX resistance is quite a common issue in clinical practice. There are some premises that aryl hydrocarbon receptor (AhR) gene battery may take part in MTX…