Isabel Córdova-Oriz

ORCID: 0000-0003-3272-2406 · 2 papers in corpus · active 2022-2023

Study types

  • article 2
article 2023
A Randomized Controlled Intervention Trial with Danazol to Improve Telomeric and Fertility Parameters in Women with Diminished Ovarian Reserve: A Pilot Study
·doi:10.1089/whr.2023.0013

Background: fertilization (IVF) clinics have trouble conceiving due to ovarian failure (OF), which seems to be associated to short telomeres and reduced or absent telomerase activity in their granulosa cells. Indeed, telomere pathways are i…

article 2022
P-629 A prospective, randomized, placebo-controlled pilot trial investigating telomere length dynamics and ovarian function in patients with diminished ovarian reserve (DOR) after danazol treatment
·doi:10.1093/humrep/deac107.578

Abstract Study question Could the administration of a synthetic steroid -danazol- for 3 months reactivate telomerase activity and lengthen telomeres in patients with DOR? Summary answer Danazol treatment resulted in an increase of the mean …