Introduction: Endometriosis, a chronic inflammatory disease often beginning in adolescence, significantly impacts quality of life. Delayed diagnosis contributes to prolonged suffering, educational disruption, and high healthcare costs. Prom…
This study aimed to investigate the association of adenomyosis with fertility, pregnancy and neonatal outcomes. An electronic search was conducted using the MEDLINE, PubMed and Cochrane databases up to April 2020. Seventeen observational st…
In the last decade, the microbiota, i.e., combined populations of microorganisms living inside and on the surface of the human body, has increasingly attracted attention of researchers in the medical field. Indeed, since the completion of t…
Endometriosis is a chronic inflammatory condition characterised by the growth of endometrial epithelial and stromal cells outside the uterine cavity. In addition to Sampson's theory of retrograde menstruation, endometriosis pathogenesis is …
Maternal control of inflammation is essential during pregnancy and an exaggerated response is one of the underlying causes of fetal loss. Inflammatory response is mediated by multiple factors and Toll-like receptors (TLRs) are central. Acti…
Endometriosis affects approximately 15% of reproductive aged women and is associated with chronic pelvic pain and infertility. However, the molecular mechanisms by which endometriosis impacts fertility are poorly understood. The development…
Der Tatsache, dass die Endometriose auch Jugendliche betrifft, wird häufig zu wenig Achtung geschenkt. Sie ist aber gerade in diesem Alter mit hohem Leidensdruck verbunden. Es finden sich Symptome wie chronische Bauchschmerzen, die zu häufi…
We report two women who presented with a recurrent, mildly painful, bluish nodule in the umbilicus. Both patients complained of local tenderness and occasional bleeding that increased during menstruation. Neither patient had had previous pe…
A 30-year-old primigravida experienced spontaneous uterine rupture at 18 weeks of gestation. The etiology for the rupture was an extensive, heavily decidualized adenomyosis. Although adenomyosis is relatively common, complications are rare.