David J. McLernon

ORCID: 0000-0001-8905-2429 · 10 papers in corpus
other 2026
Human reproduction open ·doi:10.1093/hropen/hoag056

STUDY QUESTION: Can a model be developed to predict natural conception leading to live birth over a period of 12 months in couples with different causes of infertility? SUMMARY ANSWER: We developed and validated a novel clinical prediction…

other 2023
Human reproduction open ·doi:10.1093/hropen/hoad003

STUDY QUESTION: Are perinatal outcomes following fresh blastocyst versus fresh cleavage stage embryo transfer (ET) different in singletons, twins, and between singleton siblings? SUMMARY ANSWER: Singleton babies conceived following fresh b…

other 2023
Human reproduction open ·doi:10.1093/hropen/hoad023

STUDY QUESTION: How should recurrent implantation failure (RIF) in patients undergoing ART be defined and managed? SUMMARY ANSWER: This is the first ESHRE good practice recommendations paper providing a definition for RIF together with rec…

case-report 2023
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dead165

STUDY QUESTION: Can two prediction models developed using data from 1999 to 2009 accurately predict the cumulative probability of live birth per woman over multiple complete cycles of IVF in an updated UK cohort? SUMMARY ANSWER: After bein…

other 2022
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deac152

STUDY QUESTION: Can we develop an IVF prediction model to estimate individualized chances of a live birth over multiple complete cycles of IVF in couples embarking on their second complete cycle of treatment? SUMMARY ANSWER: Yes, our predi…

other 2022
Human reproduction open ·doi:10.1093/hropen/hoac046

The treatment of unexplained infertility is a contentious topic that continues to attract a great deal of interest amongst clinicians, patients and policy makers. The inability to identify an underlying pathology makes it difficult to devis…

other 2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa339

STUDY QUESTION: Can we use prediction modelling to estimate the impact of coronavirus disease 2019 (COVID 19) related delay in starting IVF or ICSI in different groups of women? SUMMARY ANSWER: Yes, using a combination of three different m…

other 2019
Human Reproduction ·doi:10.1093/humrep/dez072

STUDY QUESTION: Which couples with unexplained subfertility can expect increased chances of ongoing pregnancy with IVF compared to expectant management? SUMMARY ANSWER: For couples in which the woman is under 40 years of age, IVF is associ…

other 2018
Human Reproduction ·doi:10.1093/humrep/dey317

STUDY QUESTION: How well does a previously developed dynamic prediction model perform in an external, geographical validation in terms of predicting the chances of natural conception at various points in time? SUMMARY ANSWER: The dynamic p…

other 2016
BMJ (Clinical research ed.) ·doi:10.1136/bmj.i5735

OBJECTIVE: To develop a prediction model to estimate the chances of a live birth over multiple complete cycles of in vitro fertilisation (IVF) based on a couple's specific characteristics and treatment information. DESIGN: Population based…