Lingfang Wang

No ORCID on file · 3 papers in corpus
other 2026
Integrated spatial multi-omics delineates fatty acid degradation fuels malignant evolution at the tumour periphery in cervical squamous cell carcinoma
EBioMedicine ·doi:10.1016/j.ebiom.2026.106256

BACKGROUND: Cervical squamous cell carcinoma (CSCC) exhibits profound spatial heterogeneity in evolutionary trajectories across distinct tumour foci, yet the underlying mechanisms remain poorly understood. METHODS: In this study, we perfor…

diagnostic-accuracy 2025
Multi-analyte approach combining cfDNA sequencing and protein testing for early ovarian cancer detection
iScience ·doi:10.1016/j.isci.2025.112617

Non-invasive liquid biopsy is a promising strategy for ovarian cancer (OC) detection. We evaluated the feasibility and efficacy of a multi-analyte approach combining circulating tumor DNA (ctDNA) detection with protein biomarkers for early …

other 2024
Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs
Cell death & disease ·doi:10.1038/s41419-024-06960-8

Endometrial cancer (EC) is a highly heterogeneous malignancy characterized by varied pathology and prognoses, and the heterogeneity of its cancer cells and the tumor microenvironment (TME) remains poorly understood. We conducted single-cell…