Somayeh Vafaei

No ORCID on file · 3 papers in corpus · active 2023-2026

Study types

  • other 2
  • article 1
other 2026
Phthalate Metabolite, Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine-Fibroid-Associated Phenotypes in Myometrial Stem Cell-Derived 3D Organoids
Environmental toxicology ·doi:10.1002/tox.70046

This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2-ethylhexyl) phthalate, on myometrial stem ce…

other 2025
Utilising Human Myometrial and Uterine Fibroid Stem Cell-Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids
Cell proliferation ·doi:10.1111/cpr.70025

Uterine fibroids (UFs) are the most common benign gynecologic tumours affecting women of reproductive age. This study aims to deepen the understanding of UFs complex aetiology through harnessing the power of 3D organoid models derived from …

article 2023
Prevention of uterine fibroids: Molecular mechanisms and potential clinical application
·doi:10.1016/j.jeud.2023.100018

• Uterine fibroids are the most common benign tumor to women of reproductive age with no clear pathomechanism. • Current medical therapies are designed to blunt the stimulatory effects of gonadal steroid hormones on uterine fibroids growth.…