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2025
BECLIN-1 is a multidomain protein that through dynamic interaction with a variety of partners controls autophagy and apoptosis, two processes dysregulated in cancer cells, thus playing a crucial role in cell destiny. Mutations of BECN1 gene…
2018
Cancer and stromal cells, which include (cancer-associated) fibroblasts, adipocytes, and immune cells, constitute a mixed cellular ecosystem that dynamically influences the behavior of each component, creating conditions that ultimately fav…