A Kovac

No ORCID on file · 1 paper in corpus · active 2009

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2009
Derivatives of pyrimidine, phthalimide and anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1
Chemico-biological interactions ·doi:10.1016/j.cbi.2008.10.019

Human hydroxysteroid dehydrogenase (HSD) AKR1C1 is a member of the aldo-keto reductase superfamily, and it functions mainly as a 20alpha-HSD. It catalyzes the reduction of the potent progesterone to the weak 20alpha-hydroxyprogesterone, and…