Matoy EJ

ORCID: 0009-0001-1365-7859 · 1 paper in corpus

2024

Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families reveals complex genetic architecture and phenocopies.

HGG advances ·doi:10.1016/j.xhgg.2024.100306

Approximately 20% of breast cancer cases are attributed to increased family risk, yet variation in BRCA1/2 can only explain 20%-25% of cases. Historically, only single gene or single variant testing were common in at-risk family members, an…