Lai MC

ORCID: 0000-0002-9593-5508 · 3 papers in corpus
2026
Effects of antipsychotics on brain insulin action in females: Study protocol for a placebo-controlled, crossover neuroimaging study.
PloS one ·doi:10.1371/journal.pone.0352262

Antipsychotic medications can cause serious metabolic adverse effects, including type 2 diabetes, with females disproportionally more affected than males. Recently, brain insulin resistance (IR) has been posited as a potential determinant o…

2019
hnRNPM induces translation switch under hypoxia to promote colon cancer development.
EBioMedicine ·doi:10.1016/j.ebiom.2019.02.059

BackgroundHypoxia suppresses global protein production, yet certain essential proteins are translated through alternative pathways to survive under hypoxic stress. Translation via the internal ribosome entry site (IRES) is a means to produc…

2014
Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation.
Nucleic acids research ·doi:10.1093/nar/gkt1286

Human fibroblast growth factor 9 (FGF9) is a potent mitogen involved in many physiological processes. Although FGF9 messenger RNA (mRNA) is ubiquitously expressed in embryos, FGF9 protein expression is generally low and restricted to a few …