Zhang H

PurposeTo investigate the dynamic changes of serum Anti-Müllerian Hormone (AMH) and Inhibin B (INHB) during controlled ovarian hyperstimulation (COH) in patients with polycystic ovarian syndrome (PCOS) and analyze their correlation with COH…

ObjectiveThis study aims to evaluate the role of MRI-guided hysteroscopic one-step precise resection in diagnosing suspected myometrial invasion (MI) of endometrial cancer (EC) in patients desiring fertility preservation and to analyze the …

BackgroundAssessing plasma volume is important in the management and treatment of severe acute pancreatitis (SAP). Although it is an easy and rapid method for estimating the plasma volume, the association between estimated plasma volume sta…

The uric acid (UA) to HDL-cholesterol ratio (UHR) has recently been proposed as a novel marker of cardiometabolic and inflammatory risk. This study aimed to investigate the association between UHR and infertility in U.S. women of reproducti…

STUDY BACKGROUND: Preoperative assessment of the severity of pelvic adhesions in endometriosis remains challenging. Inflammation may drive adhesion formation, and the predictive value of the neutrophil percentage-to-albumin ratio (NPAR, the…

BackgroundMatrix remodeling-associated 7 (MXRA7) plays a key role in physiological and pathological processes involving the extracellular matrix (ECM) and tissue remodeling. Recent studies have highlighted its functions in tissue injury, im…

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, often leading to dysmenorrhea and infertil…

BACKGROUND: Uterus ageing is a crucial factor contributing to decreased fertility in older women and is also implicated in menstrual disorders, endometritis, and adenomyosis. Bushen Jianpi Tiaoxue Decoction (BJTD) is a traditional Chinese m…

RESEARCH QUESTION: How does tubal endometriosis (TEM) impact the morphology and ultrastructure of tubal epithelium, and what are the underlying pathophysiological mechanisms of TEM? DESIGN: Epithelial samples of fallopian tube were collect…

OBJECTIVE: This study aimed to explore the feasibility and clinical effects of a novel hysteroscopic levonorgestrel-releasing intrauterine system (LNG-IUS) non-suture fixation at the uterine fundus. METHODS: From October 2023 to July 2024,…

Ovarian cancer, particularly epithelial ovarian cancer (EOC), is the most aggressive and lethal gynecologic malignancy, necessitating the development of innovative and potent therapies to improve its prognosis. Human polo-like kinase 1 (PLK…

BackgroundUterine fibroids present significant obstetric challenges, particularly in late pregnancy. This study compared the outcomes of cesarean section combined with myomectomy (CS+M) versus cesarean section followed by elective myomectom…

OBJECTIVE: To explore the clinical efficacy of commonly used conservative treatments for adenomyosis using both TCM and Western medicine. METHODS: 210 patients with adenomyosis were selected and divided into 3 groups: Group A (Dan'e Fukang…

AimThis study aimed to compare the diagnostic accuracy of ultrasound (US) and magnetic resonance imaging (MRI) in the detection of placenta accreta spectrum (PAS) disorders in a single tertiary care setting.Materials and methodsAll eligible…

[This corrects the article DOI: 10.3389/fgene.2025.1614573.].

Polycystic ovary syndrome (PCOS) is a common reproductive disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. The quality of oocytes in PCOS patients remains poor, leading to poor pregnancy outcomes. T…

In clinical drug development, two fundamental questions must be addressed: what is the success rate of drugs in clinical trial; how does such rate change over time. Here, a dynamic strategy for calculating clinical trial success rate (ClinS…

BackgroundCurrent advances in high-throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations…

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and incr…

BACKGROUND: Adenomyosis is often associated with abnormal uterine bleeding (AUB), which can lead to anemia. Recurrent bleeding, especially in the presence of cerebral infarction risk, may exacerbate the likelihood of cerebral infarction thr…

Study questionIs there an association between changes in endometrial thickness (EMT) following progesterone administration and pregnancy outcomes in frozen-thawed embryo transfers (FETs) at Day 3 (D3) and blastocyst stages?Summary answerEnd…

Yizheng Zu,1– 4,* Yi Xie,1– 4,* Huale Zhang,1– 4,* Lichun Chen,1– 4 Shihan Yan,1 Zhenna Wang,1 Zhuanji Fang,1– 4 Shunhe Lin,1 Jianying Yan1– 4 1College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical Universi…

PURPOSE: Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the potential association between endo…

ObjectiveThis study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer.Materials and methodsThis study included 133 patients who were treated at Beijing Obstetrics and …