Hartmut Blode

No ORCID on file · 2 papers in corpus

nonrandomized-trial 2012

Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women

Contraception ·doi:10.1016/j.contraception.2012.01.010

BACKGROUND: We evaluated the effects of cytochrome P450 3A4 (CYP3A4) induction and inhibition on steady-state pharmacokinetics of the components of a novel oral contraceptive (OC) containing estradiol valerate (E₂V) and dienogest (DNG). ST…

nonrandomized-trial 2009

Pharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogest

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception ·doi:10.1080/13625180902850039

OBJECTIVE: To evaluate the pharmacokinetics of a combined oral contraceptive (OC) containing oestradiol valerate/dienogest (E2V/DNG) administered according to a four-phasic dosing regimen with an oestrogen step-down and a progestin step-up …