Kottyan L

No ORCID on file · 4 papers in corpus · active 2022-2025

Study types

  • other 3

Condition tags

  • endometriosis 3
other 2025
Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women
Research square ·doi:10.21203/rs.3.rs-8116602/v1

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis across 14 biobanks worldwide, including 32% non-European patient participants, as part of the Global Biobank Meta-Analysis Initiative (GBMI). Ou…

other 2024
Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records
Research square ·doi:10.21203/rs.3.rs-5004325/v1

Endometriosis is a complex and heterogeneous condition affecting 10% of reproductive-age women, and yet, it often goes undiagnosed for several years. Limited observed heritability (7%) of large genetic association studies may be attributabl…

other 2024
Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women
medRxiv : the preprint server for health sciences ·doi:10.1101/2024.11.26.24316723

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis consisting of a large portion (31%) of non-European samples across 14 biobanks worldwide as part of the Global Biobank Meta-Analysis Initiative …

2022
Inference of causal relationships based on the genetics of cardiometabolic traits and conditions unique to females in >50,000 participants
·doi:10.1101/2022.02.02.22269844

Background Cardiometabolic diseases are highly comorbid and associated with poor health outcomes. However, the investigation of the relationship between the genetic predisposition to cardiometabolic diseases with the risk of conditions uniq…