Umar A

PurposeTo assess whether MUC1 peptide vaccine produces an immune response and prevents subsequent colon adenoma formation.Patients and methodsMulticenter, double-blind, placebo-controlled randomized trial in individuals age 40 to 70 with di…

Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a common autosomal dominant syndrome characterized by early age at onset, neoplastic lesions, and microsatellite instability (MSI). Because cancers with MSI…