Sutter G

ORCID: 0009-0003-5651-9207 · 1 paper in corpus

other 2022

Assessment of the safe and efficacious dose of the selective progesterone receptor modulator vilaprisan for the treatment of patients with uterine fibroids by exposure-response modelling and simulation

British journal of clinical pharmacology ·doi:10.1111/bcp.15014

AIMS: We report population pharmacokinetic (popPK) and exposure-response (E-R) analyses for efficacy (induced amenorrhoea [IA]) and safety (unbound oestradiol [E2] concentrations) of the selective progesterone receptor modulator vilaprisan.…