Wouter P. R. Verdurmen

ORCID: 0000-0002-2463-277X · 4 papers in corpus · active 2024-2025

Study types

  • review 2
  • article 1
  • other 1

Condition tags

  • endometriosis 4
  • endometrioma 1
other 2025
Artificial intelligence-based tissue segmentation and cell identification in multiplex-stained histological endometriosis sections
Human Reproduction ·doi:10.1093/humrep/deae267

STUDY QUESTION: How can we best achieve tissue segmentation and cell counting of multichannel-stained endometriosis sections to understand tissue composition? SUMMARY ANSWER: A combination of a machine learning-based tissue analysis softwa…

review 2025
Etiologies of endometriosis and model systems: is there a risk of a tunnel vision?
Frontiers in medicine ·doi:10.3389/fmed.2025.1675051

Endometriosis is the growth of endometrial-like tissue at non-uterine locations, primarily within the peritoneal cavity. The disease can have diverse presentations with superficial lesions, deep invading lesions and ovarian cysts (endometri…

article 2024
Endometriotic tissue fragments are viable after cryopreservation in an ex vivo tissue model recapitulating the fibrotic microenvironment
Human Reproduction ·doi:10.1093/humrep/deae164

STUDY QUESTION: Is it possible to establish an ex vivo endometriosis model using cryopreserved endometriotic tissue fragments? SUMMARY ANSWER: Cryopreserved endometriotic tissue fragments remain viable after thawing and during at least 3 d…

review 2024
The role of fibrosis in endometriosis: a systematic review
Human reproduction update ·doi:10.1093/humupd/dmae023

BACKGROUND: Fibrosis is an important pathological feature of endometriotic lesions of all subtypes. Fibrosis is present in and around endometriotic lesions, and a central role in its development is played by myofibroblasts, which are cells …