David M Hyman

No ORCID on file · 2 papers in corpus

nonrandomized-trial 2019

First-in-Human Phase I Study of the Activin A Inhibitor, STM 434, in Patients with Granulosa Cell Ovarian Cancer and Other Advanced Solid Tumors

Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-19-1065

PURPOSE: STM 434 is a soluble receptor ligand trap targeting activin A, a protein in the TGFβ family that plays important roles in growth, differentiation, and cancer cachexia. This study evaluated the safety, antitumor activity, and metabo…

observational 2016

Staging Lymphadenectomy in Patients With Clear Cell Carcinoma of the Ovary

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0000000000000559

OBJECTIVE: The purpose of this study was to assess the rate of lymph node (LN) metastasis in comprehensively staged ovarian clear cell carcinoma (OCCC) clinically confined to the ovary and determine factors associated with LN metastasis. M…