T Ishikawa

No ORCID on file · 4 papers in corpus
lab-animal 2000
Growth-stimulating effect of dienogest, a synthetic steroid, on rodent, canine, and primate mammary glands
Toxicology ·doi:10.1016/s0300-483x(00)00318-8

We observed hyperplasia of the mammary gland in female beagle dogs, but not in female rats and monkeys, in 91-day toxicity studies on dienogest. In order to elucidate a possible mechanism for its development and to account for this species …

lab-animal 1999
Effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats
Toxicology letters ·doi:10.1016/s0378-4274(98)00354-3

We investigated the effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats compared with that of medroxyprogesterone acetate (MPA) and danazol, in order to elucidate the reason for relativel…

lab-animal 1998
Effects of dienogest (a synthetic steroid) on coagulation, fibrinolysis, and platelet aggregation in female monkeys
Toxicology letters ·doi:10.1016/s0378-4274(98)00109-x

We investigated the effects of dienogest (0.1-10 mg/kg per day, p.o.) on coagulation, fibrinolysis and platelet aggregation in female rhesus monkeys. Then, we also examined those of medroxyprogesterone acetate (MPA, 10 mg/kg per day, p.o.) …

other 1996
Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues
International journal of cancer ·doi:10.1002/(sici)1097-0215(19960328)66:1<11::aid-ijc3>3.0.co;2-1

We generated DNA probes for CD44 variable region exons 11 (v6) to 14 (v9) and also for intronic sequences and examined the expression of aberrant CD44 transcripts in digestive tract carcinomas, colorectal adenomas and intestinal metaplasia …