Tarja Lamminen

ORCID: 0000-0002-9556-687X · 1 paper in corpus

article 2010

Novel Hydroxysteroid (17β) Dehydrogenase 1 Inhibitors Reverse Estrogen-Induced Endometrial Hyperplasia in Transgenic Mice

The American Journal of Pathology ·doi:10.2353/ajpath.2010.090325

Local estrogen production plays a key role in proliferative endometrial disorders, such as endometrial hyperplasia and cancer. Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) is an enzyme that catalyzes with high efficiency the conversion…