Nanjappa MK

ORCID: 0000-0001-5295-2220 · 2 papers in corpus
2020
Physiological genomics ·doi:10.1152/physiolgenomics.00098.2019

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of lu…

2019
Biology of reproduction ·doi:10.1093/biolre/ioz097

Enhancer of zeste homolog 2 (EZH2) is a rate-limiting catalytic subunit of a histone methyltransferase, polycomb repressive complex, which silences gene activity through the repressive histone mark H3K27me3. EZH2 is critical for epigenetic …