Laura B L Wittemans

No ORCID on file · 3 papers in corpus · active 2022-2025

Study types

  • other 2
  • meta-analysis 1

Condition tags

  • endometriosis 3
  • infertility 3
meta-analysis 2025
Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum
Nature genetics ·doi:10.1038/s41588-025-02156-8

Genome-wide association studies (GWASs) may help inform the etiology of infertility. Here, we perform GWAS meta-analyses across seven cohorts in up to 42,629 cases and 740,619 controls and identify 25 genetic risk loci for male and female i…

other 2024
Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum
medRxiv : the preprint server for health sciences ·doi:10.1101/2024.03.19.24304530

Genome-wide association studies (GWASs) may help inform treatments for infertility, whose causes remain unknown in many cases. Here we present GWAS meta-analyses across six cohorts for male and female infertility in up to 41,200 cases and 6…

other 2022
Obesity and risk of female reproductive conditions: A Mendelian randomisation study
PLoS medicine ·doi:10.1371/journal.pmed.1003679

BACKGROUND: Obesity is observationally associated with altered risk of many female reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine bleeding, endometriosis, infertility, and pregnancy-related disorde…