James M Hotaling

No ORCID on file · 7 papers in corpus
observational 2026
Translational andrology and urology ·doi:10.21037/tau-2026-0338

BACKGROUND: Though idiopathic urethral strictures are a common form of strictures, little is understood about the pathophysiology leading to their development. This retrospective cohort study sought to analyze the risk of environmental toxi…

observational 2025
Journal of the Endocrine Society ·doi:10.1210/jendso/bvaf030

BACKGROUND: Nonobstructive azoospermia (NOA) and primary ovarian insufficiency (POI) have common genetics that may also predispose patients to cancer risk. OBJECTIVES: We hypothesized that NOA or severe oligozoospermia and the risk of male…

observational 2023
F&S science ·doi:10.1016/j.xfss.2023.09.001

OBJECTIVE: To investigate the power of DNA methylation variability in sperm cells in assessing male fertility potential. DESIGN: Retrospective cohort. SETTING: Fertility care centers. PATIENTS: Male patients seeking infertility treatment…

observational 2022
F&S reports ·doi:10.1016/j.xfre.2022.03.004

OBJECTIVE: To describe the prevalence and treatment characteristics of assisted reproductive technology (ART) cycles involving specific male factor infertility diagnoses in the United States. DESIGN: Cross-sectional analysis of ART cycles …

observational 2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab133

STUDY QUESTION: What thresholds for total sperm count, sperm concentration, progressive motility, and total progressive motile sperm count (TPMC) are associated with earlier time-to-conception in couples undergoing fertility evaluation? SU…

observational 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.09.013

OBJECTIVE: To evaluate the relationship between epigenetic patterns in sperm and fecundity. DESIGN: Prospective study. SETTING: Academic andrology and in vitro fertilization laboratory. PATIENT(S): Twenty-seven semen samples from couples…

observational 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.10.048

OBJECTIVE: To assess the effects of both male and female body mass index (BMI), individually and combined, on IVF outcomes. DESIGN: Prospective cohort study. SETTING: University fertility center. PATIENT(S): All couples undergoing first …