Danushi Rajapakse

ORCID: 0009-0002-4096-822X · 2 papers in corpus

review

How is the "most bothersome symptom" construct measured across health conditions? A systematic review of patient-reported outcome measures

Patient related outcome measures ·doi:10.1080/1179271X.2026.2732841

OBJECTIVE: Patient-reported outcome measures (PROMs) capture patients' experiences and perspectives of symptoms. One approach involves measuring the "most bothersome symptom," an outcome recommended in some regulatory guidance and core outc…

other 2024

The "most bothersome symptom" construct: A qualitative study of Australians living with endometriosis

Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.14876

INTRODUCTION: "Improvement in the most bothersome symptom" was recently selected as a core outcome for endometriosis intervention trials. This study aimed to explore the applicability of the construct of "symptom bother" in representing the…