Hodgkinson K

ORCID: 0000-0002-2168-0389 · 3 papers in corpus
2023
Beyond Sterilization: A Comprehensive Review on the Safety and Efficacy of Opportunistic Salpingectomy as a Preventative Strategy for Ovarian Cancer.
Current oncology (Toronto, Ont.) ·doi:10.3390/curroncol30120739

Ovarian cancer (OC) is Canada's third most common gynecological cancer, with an estimated 3000 new cases and 1950 deaths projected in 2022. No effective screening has been found to identify OC, especially the most common subtype, high-grade…

2018
GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer.
Oncogene ·doi:10.1038/s41388-018-0377-y

Estrogenic hormone replacement therapy increases the risk of developing ovarian cancer, and estrogen promotes tumour initiation and growth in mouse models of this disease. GREB1 (Growth regulation by estrogen in breast cancer 1) is an ESR1 …

2013
Estrogen responsiveness of the TFIID subunit TAF4B in the normal mouse ovary and in ovarian tumors.
Biology of reproduction ·doi:10.1095/biolreprod.113.111336

Estrogen signaling in the ovary is a fundamental component of normal ovarian function, and evidence also indicates that excessive estrogen is a risk factor for ovarian cancer. We have previously demonstrated that the gonadally enriched TFII…