Chaoying Wang

No ORCID on file · 2 papers in corpus
lab-animal 2026
Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202601614r

Ovarian senescence is accompanied by inflammatory responses, yet the underlying mechanism remains incompletely elucidated. In this study, transcriptome sequencing was performed on ovarian granulosa cells from advanced-age patients and norma…

lab-animal 2026
NR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian Protection
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202603415r

Obesity triggers ovarian dysfunction and female infertility accompanied by granulosa cell damage. Ferroptosis, iron-dependent lipid peroxidation-mediated cell death, participates in multiple reproductive diseases, yet the molecular cascade …