Xian-Hua Lin — Endo Lab

review 2026

Targeting the Immune Network in Endometriosis: A Comprehensive Review of Pathogenesis, Immunomodulation, and Emerging Therapies

Pharmaceuticals (Basel, Switzerland) ·doi:10.3390/ph19071074

Endometriosis is a chronic inflammatory disease characterized by the ectopic growth of endometrial-like tissue and is closely associated with pain and infertility. This review summarizes current evidence on immune dysregulation and emerging…

other 2025

Genetic Association and Drug Target Exploration Between Inflammation-Related Proteins and the Risk of Primary Ovarian Insufficiency

Journal of inflammation research ·doi:10.2147/jir.s538776

PURPOSE: Primary ovarian insufficiency (POI) exhibits ovarian dysfunction characteristics, which develops from diminished ovarian reserve (DOR). However, the pathogenesis remains unclear. In this study, we aimed to analyze the causal relati…

observational 2024

High androgen level during controlled ovarian stimulation cycle impairs endometrial receptivity in PCOS patients

Scientific reports ·doi:10.1038/s41598-024-74295-7

PCOS is one of the most common endocrine disorders among women of reproductive age. While the mechanism involved is not yet fully characterized. Our study aims to examine the pregnancy outcomes of embryo transfers in women with PCOS after p…

other 2022

Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial

BMJ open ·doi:10.1136/bmjopen-2022-063030

INTRODUCTION: Conventional intracytoplasmic sperm injection (ICSI) is a widely used treatment for couples with severe male infertility. However, there are controversies regarding the selection and the damage to gametes during the ICSI proce…