Gail Jarvik

No ORCID on file · 3 papers in corpus · active 2024

Study types

  • other 2
  • preprint 1

Condition tags

  • endometriosis 3
other 2024
Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records
Research square ·doi:10.21203/rs.3.rs-5004325/v1

Endometriosis is a complex and heterogeneous condition affecting 10% of reproductive-age women, and yet, it often goes undiagnosed for several years. Limited observed heritability (7%) of large genetic association studies may be attributabl…

preprint 2024
Enhancing Genetic Association Power in Endometriosis through Unsupervised Clustering of Clinical Subtypes Identified from Electronic Health Records
medRxiv : the preprint server for health sciences ·doi:10.1101/2024.04.22.24306092

BACKGROUND: Endometriosis affects 10% of reproductive-age women, and yet, it goes undiagnosed for 3.6 years on average after symptoms onset. Despite large GWAS meta-analyses (N > 750,000), only a few dozen causal loci have been identified. …

other 2024
Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women
medRxiv : the preprint server for health sciences ·doi:10.1101/2024.11.26.24316723

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis consisting of a large portion (31%) of non-European samples across 14 biobanks worldwide as part of the Global Biobank Meta-Analysis Initiative …