Hammock BD

ORCID: 0000-0003-1408-8317 · 2 papers in corpus

2023

Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer.

Oncogene ·doi:10.1038/s41388-022-02566-6

Castration-resistant prostate cancer (CRPC) is the main driving force of mortality in prostate cancer patients. Among the parameters contributing to the progression of CRPC and treatment failure, elevation of the steroidogenic enzyme AKR1C3…

2021

Carcinogenesis: Failure of resolution of inflammation?

Pharmacology & therapeutics ·doi:10.1016/j.pharmthera.2020.107670

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a key characteristic of carcinogens. However, the failure of resolution of inflammation in cancer is only recently being understood. Products of arachid…