Melrose J

ORCID: 0000-0001-9237-0524 · 3 papers in corpus
2023
An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics.
JOR spine ·doi:10.1002/jsp2.1230

Animal models have been invaluable in the identification of molecular events occurring in and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets have been identified. Some outstanding animal models (mur…

2023
Intervertebral disc degeneration and how it leads to low back pain.
JOR spine ·doi:10.1002/jsp2.1231

The purpose of this review was to evaluate data generated by animal models of intervertebral disc (IVD) degeneration published in the last decade and show how this has made invaluable contributions to the identification of molecular events …

2023
The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline.
Antioxidants (Basel, Switzerland) ·doi:10.3390/antiox12030663

Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-inflammatory, antiviral, and antibacterial cell protective profiles. They have received considerable attention as potential therapeutic agents in biomedicin…