Kubatka P

ORCID: 0000-0003-4312-5076 · 4 papers in corpus
2026
The specificity trap in routine tumor biomarker interpretation: Advancing the 3PM-based clinical decision framework to benefits of patients.
The EPMA journal ·doi:10.1007/s13167-026-00466-3

Routine tumor biomarkers remain among the most accessible tools in oncology. Yet, their clinical value is frequently weakened by a persistent specificity trap: abnormal results are often treated as cancer-specific signals, whereas normal re…

2025
Canine Endometrial Mesenchymal Stem Cells: Characterization and Functional Assessment for Cartilage Repair.
International journal of molecular sciences ·doi:10.3390/ijms26168091

Endometrial mesenchymal stem cells (eMSCs) are a novel and biologically potent source of multipotent stromal cells with potential beyond reproductive medicine. This study explored their phenotypic profile, trilineage differentiation, and th…

2020
Rho GTPases in Gynecologic Cancers: In-Depth Analysis toward the Paradigm Change from Reactive to Predictive, Preventive, and Personalized Medical Approach Benefiting the Patient and Healthcare.
Cancers ·doi:10.3390/cancers12051292

Rho guanosine triphospatases (GTPases) resemble a conserved family of GTP-binding proteins regulating actin cytoskeleton dynamics and several signaling pathways central for the cell. Rho GTPases create a so-called Ras-superfamily of GTPases…

2019
Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection.
International journal of molecular sciences ·doi:10.3390/ijms20123017

Calcium (Ca2+) signaling and the modulation of intracellular calcium ([Ca2+]i) levels play critical roles in several key processes that regulate cellular survival, growth, differentiation, metabolism, and death in normal cells. On the other…