Yu Ren

ORCID: 0000-0002-8582-680X · 3 papers in corpus
review 2024
Alarmins and their pivotal role in the pathogenesis of spontaneous abortion: insights for therapeutic intervention
European journal of medical research ·doi:10.1186/s40001-024-02236-1

Alarmins are a class of molecules released when affected cells damaged or undergo apoptosis. They contain various chemotactic and immunomodulatory proteins or peptides. These molecules regulate the immune response by interacting with patter…

review 2023
HMGB1: a double-edged sword and therapeutic target in the female reproductive system
Frontiers in immunology ·doi:10.3389/fimmu.2023.1238785

HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin associated transcription factor. It is present in the nucleus of eukaryotes and can be actively secreted or passively released by kinds of cells. HMGB1…

lab-animal 2018
Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway
OncoTargets and therapy ·doi:10.2147/ott.s180785

PURPOSE: Polydatin, a stilbenoid glucoside of a resveratrol derivative, has many biological functions, including antitumor effects. However, the antitumor effects of polydatin in renal cell carcinoma (RCC) have not been investigated. MATER…