Cantin L

No ORCID on file · 1 paper in corpus

2006

Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.

Protein science : a publication of the Protein Society ·doi:10.1110/ps.051905906

Androgens exert their effects by binding to the highly specific androgen receptor (AR). In addition to natural potent androgens, AR binds a variety of synthetic agonist or antagonist molecules with different affinities. To identify molecula…