Alexey Polonikov

The work was performed to assess the relationship of single-nucleotide polymorphisms (SNPs), which determine the concentration of sex hormones (confirmed in previously performed genome-wide studies (GWASs)), with the risk of endometrial hyp…

In this study we searched for correlations between polymorphic variants that determine sex hormone-binding globulin concentration (SHBGcon) and uterine fibroids (UFs). The work was performed on a sample of 1542 women (569 with UFs and 973 w…

The main goal of this study was to consider the role of obesity/overweight as a potential modifier of associations between gene single nucleotide polymorphisms (SNPs) affecting the sex hormone-binding globulin level (SHBGlevel) and uterine …

We aimed to explore the potential link of maternal age at menarche (mAAM) gene polymorphisms with risk of the fetal growth restriction (FGR). This case (FGR)-control (FGR free) study included 904 women (273 FGR and 631 control) in the third…

In this study, the association between maternal age at menarche (AAM)-related polymorphisms and offspring birth weight (BW) was studied. The work was performed on a sample of 716 pregnant women and their newborns. All pregnant women underwe…

В исследование были включены 603 пациентки с миомой матки и 398 женщин контрольной группы. Генотипирование однонуклеотидных полиморфизмов (SNP) генов сигнального каскада арил-гидрокарбонового рецептора (rs2066853 AHR, rs2292596 AHRR, rs2228…

Research questionAre the candidate genes for age at menarche associated with a risk of endometriosis?DesignFifty-two candidate single nucleotide polymorphisms (SNP) for age at menarche, their gene-gene and gene-environment interactions were…

A total of 603 females with uterine fibroids and 398 healthy individuals from Central Russia were recruited for the study. Genotyping of single nucleotide polymorphisms (SNPs) of the aryl hydrocarbon receptor signaling pathway genes (rs2066…

Основные этиопатогенетические механизмы развития гиперплазии эндометрия, их факторов риска и генетических детерминантах

Систематический анализ данных о молекулярно-генетических детерминантах развития эндометриоза, имеющихся в современной литературе

Систематический анализ данных об этиопатогенезе, факторах риска эндометриоза, имеющихся в современной литературе. Основные этиологические гипотезы, молекулярные механизмы формирования эндометриоза, факторы риска заболевания