O'Leary JJ

ORCID: 0000-0001-7311-9326 · 2 papers in corpus

2026

Lipid metabolism in γδ T-cell activation: Implications for immunotherapy in ovarian cancer.

Translational oncology ·doi:10.1016/j.tranon.2026.102953

Ovarian cancer (OC) remains a leading cause of cancer-related mortality among women worldwide, largely due to asymptomatic progression, late-stage diagnosis, therapeutic resistance, and profound immunosuppression within the tumor microenvir…

2025

Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities.

Cells ·doi:10.3390/cells14201594

Epithelial-mesenchymal transition (EMT) and inflammasome signalling are intercon-nected processes which underpin tumour progression, metastasis, and therapeutic re-sistance. Inflammasomes such as NLRP3 encourage pro-inflammatory states (IL-…