Shaw P

ORCID: 0000-0002-0783-9410 · 4 papers in corpus
2024
Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer.
Cancer letters ·doi:10.1016/j.canlet.2024.217357

Ovarian cancer (OC) accounts for the highest mortality rates among all gynecologic malignancies. The high mortality of OC is often associated with delayed detection, prolonged latency, enhanced metastatic potential, acquired drug resistance…

2019
Evaluation of cardiovascular risk in a lung cancer screening cohort.
Thorax ·doi:10.1136/thoraxjnl-2018-212812

IntroductionLung cancer screening (LCS) by low-dose computed tomography (LDCT) offers an opportunity to impact both lung cancer and coronary heart disease mortality through detection of coronary artery calcification (CAC). Here, we explore …

2018
Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study.
Cancer prevention research (Philadelphia, Pa.) ·doi:10.1158/1940-6207.capr-18-0009

The prognosis of women diagnosed with invasive high-grade serous ovarian carcinoma (HGSC) is poor. More information about serous tubal intraepithelial carcinoma (STIC) and serous tubal intraepithelial lesions (STIL), putative precursor lesi…

other 2014
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy
The Journal of Pathology ·doi:10.1002/path.4315

Up-regulated expression of telomerase reverse transcriptase (TERT) and subsequent maintenance of telomere length are essential in tumour development. Recent studies have implicated somatic gain-of-function mutations at the TERT promoter as …