Townsend TR

No ORCID on file · 3 papers in corpus · active 2011-2019

Study types

  • other 1

Condition tags

  • endometriosis 1
2019
Water-Soluble Nanoconjugate for Enhanced Cellular Delivery of Receptor-Targeted Magnetic Resonance Contrast Agents.
Bioconjugate chemistry ·doi:10.1021/acs.bioconjchem.9b00640

ProGlo is an efficient steroid receptor-targeted magnetic resonance (MR) imaging contrast agent (CA). It has been shown to bind to the progesterone receptor (PR) and produce enhanced image contrast in PR-positive cells and tissues in vitro …

2014
Progesterone-targeted magnetic resonance imaging probes.
Bioconjugate chemistry ·doi:10.1021/bc500265h

Determination of progesterone receptor (PR) status in hormone-dependent diseases is essential in ascertaining disease prognosis and monitoring treatment response. The development of a noninvasive means of monitoring these processes would ha…

other 2011
Synthesis and biological evaluation of water-soluble progesterone-conjugated probes for magnetic resonance imaging of hormone related cancers
Bioconjugate chemistry ·doi:10.1021/bc2003555

Progesterone receptor (PR) is strongly associated with disease prognosis and therapeutic efficacy in hormone-related diseases such as endometriosis and breast, ovarian, and uterine cancers. Receptor status is currently determined by immunoh…