Stefano Signorini

No ORCID on file · 4 papers in corpus
observational 2021
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa324

STUDY QUESTION: Is there an association between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and fecundability and infertility among Seveso women and their daughters? SUMMARY ANSWER: TCDD exposure is associated with a decrease in fe…

observational 2018
International journal of epidemiology ·doi:10.1093/ije/dyy165

BACKGROUND: 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is proposed to interfere with fetal growth via altered activity of the aryl hydrocarbon receptor (protein: AHR; gene: AHR) pathway which regulates diverse biological and developmenta…

review 2018
Environment international ·doi:10.1016/j.envint.2018.08.051

A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a known human carcinogen and potent endocrine disruptor. It is highly lipophilic and h…

observational 2008
Environmental health perspectives ·doi:10.1289/ehp.10399

BACKGROUND: Environmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In 1976 an accident exposed residents in Seveso, Italy, to 2,3,7,8-tetrachlorodibenzo-…