Jewell CM

No ORCID on file · 2 papers in corpus
2022
Microtentacle Formation in Ovarian Carcinoma.
Cancers ·doi:10.3390/cancers14030800

BackgroundThe development of chemoresistance to paclitaxel and carboplatin represents a major therapeutic challenge in ovarian cancer, a disease frequently characterized by malignant ascites and extrapelvic metastasis. Microtentacles (McTNs…

2017
Generating diversity in human glucocorticoid signaling through a racially diverse polymorphism in the beta isoform of the glucocorticoid receptor.
Laboratory investigation; a journal of technical methods and pathology ·doi:10.1038/labinvest.2017.76

Alternative splicing of the human glucocorticoid receptor gene generates two isoforms, hGRα and hGRβ. hGRβ functions as a dominant-negative regulator of hGRα activity and but also has inherent transcriptional activity, collectively altering…