The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential for the survival of th…
Study questionWhat are the outcomes of pregnancies exposed to hydroxychloroquine (HCQ) in women with a history of recurrent pregnancy loss (RPL), and what factors predict the course of these pregnancies beyond the first trimester?Summary an…
Background Recurrent miscarriage (RM) is a frequent condition affecting about 1–3 % of couples and is one of the most frustrating and difficult areas in reproductive medicine since the etiology is often unknown and evidence-based diagnosis …
Endometriosis is an inflammatory oestrogen-dependent chronic disease and is mainly expressed by pain and increased infertility. Several studies showed an increased prevalence of autoimmune systemic diseases and various autoantibodies in end…
The molecular responses to hormonal stimuli in the endometrium are modulated at the transcriptional and post-transcriptional stages. Any imbalance in cellular and molecular endometrial homeostasis may lead to gynecological disorders. MicroR…
BACKGROUND: Endometriosis is a multifactorial pathology dependent on intrinsic and extrinsic factors, but the immune deregulation seems to play a pivotal role. In endometriosis-associated infertility, this could raise the benefit of immunom…
Research questionWhat are the effects of ulipristal acetate (UPA) on the expression of endometrial proliferation and maturation markers?DesignA total of 45 endometrium-containing blocks of hysterectomy samples from non-menopausal women with…