Gao F

No ORCID on file · 31 papers in corpus
2017
Development of a Whole Slide Imaging System on Smartphones and Evaluation With Frozen Section Samples.
JMIR mHealth and uHealth ·doi:10.2196/mhealth.8242

BackgroundThe aim was to develop scalable Whole Slide Imaging (sWSI), a WSI system based on mainstream smartphones coupled with regular optical microscopes. This ultra-low-cost solution should offer diagnostic-ready imaging quality on par w…

2014
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
Biomolecular concepts ·doi:10.1515/bmc-2013-0036

DNA methylation at cytosines is an important epigenetic modification that participates in gene expression regulation without changing the original DNA sequence. With the rapid progress of high-throughput sequencing techniques, whole-genome …

2014
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Cell reports ·doi:10.1016/j.celrep.2014.03.047

Somatic mutations in exon 2 of the RNA polymerase II transcriptional Mediator subunit MED12 occur at very high frequency (∼70%) in uterine leiomyomas. However, the influence of these mutations on Mediator function and the molecular basis fo…

2012
Overexpression of cyclin D3 improves decidualization defects in Hoxa-10(-/-) mice.
Endocrinology ·doi:10.1210/en.2012-1528

Uterine decidualization, a crucial process for implantation, is a tightly regulated process encompassing proliferation, differentiation, and polyploidization of uterine stromal cells. Hoxa (Homeobox A)-10, a homeobox transcription factor, i…

2012
The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways.
Oncogene ·doi:10.1038/onc.2011.213

Ovarian cancers migrate and metastasize over the surface of the peritoneal cavity. Consequently, dysregulation of mechanisms that limit cell migration may be particularly important in the pathogenesis of the disease. ARHI is an imprinted tu…

2010
High density of peritumoral lymphatic vessels is a potential prognostic marker of endometrial carcinoma: a clinical immunohistochemical method study.
BMC cancer ·doi:10.1186/1471-2407-10-131

BackgroundThe lymphatic system is a major route for cancer cell dissemination and also a potential target for antitumor therapy. To investigate whether increased lymphatic vessel density (LVD) is a prognostic factor for nodal metastasis and…