Takiko Daikoku

ORCID: 0000-0002-6280-8502 · 8 papers in corpus · active 2007-2020

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
  • infertility 1
2020
Adolescent Dietary Habit-induced Obstetric and Gynecologic Disease (ADHOGD) as a New Hypothesis-Possible Involvement of Clock System.
Nutrients ·doi:10.3390/nu12051294

There are growing concerns that poor dietary behaviors at young ages will increase the future risk of chronic diseases in adulthood. We found that female college students who skipped breakfast had higher incidences of dysmenorrhea and irreg…

2019
Time Restriction of Food Intake During the Circadian Cycle Is a Possible Regulator of Reproductive Function in Postadolescent Female Rats.
Current developments in nutrition ·doi:10.1093/cdn/nzy093

BackgroundWe previously reported that skipping breakfast is associated with menstrual disorders of female college students during postadolescent maturation.ObjectiveIn this study, we investigated the effects of meal timing during circadian …

2017
Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma.
PloS one ·doi:10.1371/journal.pone.0188641

Although histological grade and muscular invasion are related to the malignant behaviors of endometrial endometrioid carcinoma, lymphatic and/or distant metastases are unexpectedly encountered, even in patients in the low-risk group. To re-…

2014
Lactoferrin-iCre: a new mouse line to study uterine epithelial gene function.
Endocrinology ·doi:10.1210/en.2014-1265

Transgenic animal models are valuable for studying gene function in various tissue compartments. Mice with conditional deletion of genes in the uterus using the Cre-loxP system serve as powerful tools to study uterine biology. The uterus is…

article 2010
Posters * Endometriosis, Endometrium and Implantation
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

2010
Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1009324107

Immunophilin FK506-binding protein 52 (FKBP52) is a cochaperone that binds to the progesterone receptor (PR) to optimize progesterone (P(4))-PR signaling. We recently showed that Fkbp52-deficient (Fkbp52(-/-)) mice have reduced uterine PR r…

article 2008
Deficiency of Immunophilin FKBP52 Promotes Endometriosis
The American journal of pathology ·doi:10.2353/ajpath.2008.080527

Endometriosis is a common gynecological disease that affects approximately 10% of women of childbearing age. It is characterized by endometrial growth outside the uterus and often results in inflamed lesions, pain, and reduced fertility. Al…

other 2007
FKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specific
The Journal of clinical investigation ·doi:10.1172/JCI31622

Immunophilin FKBP52 serves as a cochaperone to govern normal progesterone (P(4)) receptor (PR) function. Using Fkbp52(-/-) mice, we show intriguing aspects of uterine P(4)/PR signaling during pregnancy. Implantation failure is the major phe…