Stephen C. Phillips

The pathophysiology of endometriosis remains unclear but involves a complex interaction between ectopic endometrium and host peritoneal tissues. We hypothesized that disruption of this interaction would suppress endometriotic lesion formati…

BACKGROUND: Women with endometriosis have elevated levels of cyclooxygenase-2 (COX-2) in peritoneal macrophages and endometriotic tissue. Inhibition of COX-2 has been shown to reduce inflammation, angiogenesis and cellular proliferation. It…

Objective: We aimed to identify genes in normal human eutopic endometrium which respond to ovarian steroid hormone stimulation. We identify factors of possible interest in the pathogenesis of endometriosis.Design: The growth of ectopic endo…