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Background: Endocrine-disrupting compounds (EDCs) are widely believed to play an important role in the occurrence and development of a variety of endocrine-related diseases, especially in common gynecological endocrine diseases such as endo…
Endometriosis is a chronic estrogen-dependent inflammatory disease that significantly affects women's health. Polygala fallax Hemsl. (PFH), a traditional Zhuang medicine, has been frequently used for gynecological disorders. This study inve…
Objective: The objective of this study was to explore the inhibitory effect of total flavonoids of Polygala fallax Hemsl (PFHF) on human ectopic endometrial stromal cells (HEcESCs) and its mechanism. Design: The apoptosis, cell cycle, migra…
Background: The expression of homeobox A10 (HOXA10) in endometrial stromal cells is regulated by steroid hormones, especially by estrogen. As a precursor molecule of estrogen, abnormal cholesterol metabolism is significantly positively corr…
Abstract In endometriosis, an aberrant immune response in the peritoneal environment is evident, but the underlying mechanism remains unclear. In recent years, some emerging data support an important role for the changes in intracellular me…
e17090 Background: Ovarian clear cell carcinoma is one kind of Epithelial ovarian carcinoma and is considered high-grade tumor. This retrospective analysis aimed to evaluate the clinical and pathologic features and to determine prognostic v…
Objective To investigate the clinical characteristics and prognostic factors in the patients with ovarian clear cell adenocarcinoma(OCCA).Methods Medical records of 121 patients with OCCA treated in our hospital from February 1999 to Septem…
It is believed that ovarian endometriosis may be generated by a celomic metaplastic process from existing epithelium in the ovary. However, no morphologic evidence of metaplastic process has been described. In this study, we intended to ide…