Jeremy Chase Crawford

ORCID: 0000-0003-4096-6048 · 1 paper in corpus · active 2021
2021
Common trajectories of highly effective CD19-specific CAR T cells identified by endogenous T cell receptor lineages
·doi:10.1101/2021.12.05.21266287

Current chimeric antigen receptor-modified (CAR) T cell therapy products are evaluated in bulk, without assessment of the possible heterogeneity in effector potential between cells. Conceivably, only a subset of the pre-infusion product dif…