Tyler J Carpenter

No ORCID on file · 3 papers in corpus
other 2025
The Human Myometrial Transcriptome and the DNA Methylome of Testosterone-treated Patients Resemble the Myometria from Fibroid Patients
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01893-9

Uterine fibroids, or leiomyomas, are noncancerous tumors of the myometrium and the most common tumors in women, with a cumulative incidence of approximately 80% by age 50. Currently, hysterectomy is the only definitive cure, and effective n…

other 2021
Transcriptome Analyses of Myometrium from Fibroid Patients Reveals Phenotypic Differences Compared to Non-Diseased Myometrium
International journal of molecular sciences ·doi:10.3390/ijms22073618

Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the myometria of uterine fibroid patients represent truly non-disease control tissues. We a…

lab-animal 2020
Putative human myometrial and fibroid stem-like cells have mesenchymal stem cell and endometrial stromal cell properties
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dez247

STUDY QUESTION: Can endometrial stromal stem/progenitor cell markers, SUSD2 and CD146/CD140b, enrich for human myometrial and fibroid stem/progenitor cells? SUMMARY ANSWER: SUSD2 enriches for myometrial and fibroid cells that have mesenchy…