Donna D. Baird

BACKGROUND: While there is evidence that vitamin D deficiency is associated with long menstrual cycles, delayed ovulation, and reduced fertility, it is yet unknown if increasing vitamin D levels can regulate menstrual cycles, and thus possi…

BACKGROUND: Using menstrual products is a part of managing menstrual bleeding. Product use may represent individual, social, and economic influences. A few studies on menstrual product use from specific regions in the United States reported…

BACKGROUND: Use of menstrual tracking data to understand abnormal bleeding patterns has been limited because of lack of incorporation of key demographic and health characteristics and confirmation of menstrual tracking accuracy. OBJECTIVE:…

OBJECTIVE: Fibroid treatments that have few side-effects and can preserve fertility are a clinical priority. We studied the association between serum vitamin D and uterine fibroid growth, incidence, and loss. DESIGN: A prospective community…

BackgroundUterine leiomyomata (UL) are the leading indication for hysterectomy in the United States. Dietary supplementation with lycopene was associated with reduced size and incidence of oviduct leiomyoma in the Japanese quail. Two US pro…

Study questionIs pre-conception 25(OH)D associated with the per cycle probability of conception, i.e fecundability, in a prospective cohort study?Summary answerThere are suggestive associations of high 25(OH)D (at least 50 ng/ml) with incre…

ObjectiveThe aim of the study was to examine the associations between 25-hydroxyvitamin D (25(OH)D) and biomarkers of ovarian reserve in a large community-based sample of women.MethodsIn 2010 to 2016, women aged 30 to 44 years without any k…

ImportanceDespite lack of evidence of their utility, biomarkers of ovarian reserve are being promoted as potential markers of reproductive potential.ObjectiveTo determine the associations between biomarkers of ovarian reserve and reproducti…

We sought to determine the relationship of fibroids to pregnancy loss in a prospective cohort in which fibroid status was uniformly documented in early pregnancy. Participants had an intake interview, transvaginal ultrasonography, computer-…

ObjectiveTo characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women.DesignCross-sectional study.SettingNot applicable.Patient(s)A total of 1,6…

BackgroundPhytoestrogen exposure from soy formula feeding during infancy may disrupt reproductive system development, resulting in altered menstrual bleeding in adulthood.MethodsWe investigated this relationship in a cohort of 1,696 young A…

Study questionHow well can a single baseline ultrasound assessment of fibroid burden (presence or absence of fibroids and size of largest, if present) predict future probability of having a major uterine procedure?Summary answerDuring an 8-…

Use of personal care products is widespread in the United States but tends to be greater among African Americans than whites. Of special concern is the possible hazard of absorption of chemicals with estrogenic activity (EA) or anti-EA (AEA…

OBJECTIVE: Vitamin D has been linked to antimüllerian hormone levels, suggesting a possible association with greater ovarian reserve, but large population-based studies are lacking. Our objective was to explore the association between vitam…

IntroductionDespite estimates of a high prevalence of deep dyspareunia (DD) among women in the United States, risk factors for this important area of sexual dysfunction have been largely understudied.AimsThe purpose of this study was to exa…

ObjectivesTo evaluate intraobserver variability of fibroid sonographic measurements and apply this factor to fibroid growth assessment.MethodsStudy participants were African American women aged 23 to 34 years who had never had a diagnosis o…

ProblemUterine leiomyomata are the most common reproductive tumor in women, and their cause is not known.Methods of studyPlasma samples from 155 women (74 with and 81 without ultrasound-confirmed leiomyoma) from a new study of leiomyoma ris…

High serum follicle-stimulating hormone (FSH) levels have been associated with diminished ovarian reserve; however, the association between high urinary FSH and reduced natural fertility has yet to be established. We sought to characterize …

BackgroundUterine leiomyomata (fibroids) are hormonally responsive tumors, but little is known about risk factors. Early-life exposures may influence uterine development and subsequent response to hormones in adulthood. An earlier analysis …

BackgroundPerfluorinated compounds are ubiquitous pollutants; epidemiologic data suggest they may be associated with adverse health outcomes, including subfecundity. We examined subfecundity in relation to 2 perfluorinated compounds-perfluo…

ObjectiveTo generate estimates of the association between markers of ovarian aging and natural fertility in a community sample at risk for ovarian aging.MethodsWomen aged 30-44 years with no history of infertility who had been trying to con…

Aims/hypothesisWe assessed the effects of type 1 diabetes and type 2 diabetes on fecundability (as manifest by increased time-to-pregnancy [TTP]) in a large cohort of pregnant women.MethodsThis study is based on the Norwegian Mother and Chi…

BACKGROUND Late implantation and the pattern of early rise in hCG have been associated with early pregnancy loss. We explored factors that might be predictive of these markers of poor embryonic health in spontaneously conceived pregnancies.…

BACKGROUND: Women are often asked to recall the first day of their last menstrual period (LMP date) in a clinic setting (i.e., pregnancy dating, x-rays). There are no data supporting the validity of these reports. METHODS: Using data from a…