Alexander de Giorgio-Miller

No ORCID on file · 1 paper in corpus · active 2008

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2008
The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982)
The Journal of pharmacology and experimental therapeutics ·doi:10.1124/jpet.108.140467

The progesterone receptor (PR) is an important regulator of endometrial function. Blockade of PR function has been recognized as the potential basis for preventing gynecological conditions such as endometriosis and uterine fibroids. In this…